Depression accelerates the aging of human cells by shortening its special sections of DNA that protect the molecule from damage. This is stated in an article published in the Molecular Psychiatry journal.
Mental anguish experienced by people suffering from depression, significantly aggravate “fraying” of the human body, accelerating its aging .
Scientists have measured the length of telomeres in about 1,900 people suffering from major depressive disorder at some time in their lives, and 500 people who were not likely to be depressed. The age of the participants was 18-65 years.
Telomeres are the end portions of chromosomes located in the nucleus of every cell in the human body. Telomeres protect DNA from damage. With each cell division, they become shorter when their length is not sufficient for the new division, the cell dies.
The scientists have found that telomeres in those who suffer from depressive disorders, were shorter than in healthy participants. At the same time, the stronger were the symptoms of a mental disorder and the longer they are kept, the shorter telomeres were.
The researchers believe that their findings may explain why people who were depressed are more prone to diseases that usually come with age – dementia, cancer, diabetes type 2.
The survival in prostate cancer depends on the patient’s body weight. Overweight at diagnosis is associated with an increased risk of death from this disease.
A new prognostic factor reported by the medical clinic Kaiser Permanente. The study reviewed the records of 750 patients who had undergone radical prostatectomy surgery due to prostate malignant neoplasm. The analysis showed that the chance to survive for two years after surgery was 1.5 times higher in patients without excess weight and obesity. Furthermore, the degree of aggressiveness of the tumor is also directly dependent on the body weight index.
Overweight in adolescence also increases the risk of cancer of the esophagus in the future twice.
Israeli scientists studied data on the health of one million 17-year-old boys who passed a medical examination for military service. The experts compared the body weight index of study participants with the data base of the National Cancer Registry to determine which of volunteers later appears to get dangerous disease.
The analysis showed that the weight and the social status of a person under 17 years affect the risk of developing esophageal cancer in later life. For example, overweight raised the risk by 2.1 times and low socio-economic status – by 2.2 times. This is due to characteristics of food (in particular, the consumption of salt) and smoking which are factors of gastric cancer.
Larva of pork tapeworm – the main cause of cysticercosis can be easily eleminated with albendazole (brand name Albenza).
Cysticercosis – worm infection caused by larva of pork tapeworm – Cysticercus cellulosae, leading to the damage of skin, hypoderm, muscles, brain, spinal cord, eyes and sometimes internal organs and bones. It looks like a formation in the form of a bubble with a diameter of 5-15 mm, containing screwed scolex. Read more
Enterobiasis is the most common type of worm infestations. Pinworm (Enterobius) is thin white worm, living as a parasite in the gut and causing Enterobiasis.
Is albendazole good for the treatment of enterobiasis? Definitely yes, because albendazole perfectly kills all kinds of pinworms.
The main symptom of enterobiasis
Itching in the anal area (usually in the evening, at night or early in the morning) is one of the most common symptoms. Read more
Liver cyst is a cavity in the liver, filled with fluid. Approximately 0.8% of the population has liver cysts. Women have this disease 3-5 times more often than men, mainly in the period between 30 and 50 years.
Echinococcus granulosus is a small tapeworm that causes the formation of hydatid cysts.
This kind of tapeworms can be successfully destroyed by albendazole – #1 anthelmintic drug
The adult worm is 2-8 mm of length and consists of a scolex with four suction cups and a rim of hooks and 3-4 body segments called proglottids. Read more
Giardiasis is a huge problem in the world of medicine at the date. Giardia infects millions of people all over the world. Two-thirds of them are children under the age of 14 years. The number of cases varies depending on compliance with health standards and social conditions, the adequacy of diagnosis. Giardiasis is difficult to identify, since there is no clinical symptoms, clearly indicating the disease.
Nevertheless it can be treated with anthelmintic drug Albenza (albendazole).
The main clinical manifestations of giardiasis: Read more
Helminthiasis is a very common type of disease. On average, one of every three people on Earth is the carrier of worms. This type of infection is extremely difficult to diagnose. Clinical symptoms are usually unnoticed, and stool tests are not always inconclusive.
However, helminthiasis is treated with albendazole without any problem.
Taking into consideration the toxicity and side effects of pharmaceutical drugs in the treatment of certain diseases is not always necessary to resort to their aid. Read more
A mass albendazole administration was successful in eliminating lymphatic filariasis in Port-au-Prince, Haiti, in 71% cases.
Lymphatic filariasisis is an infection caused by worm Wuchereria bancrofti associated with lymphedema and hydrocele. It has been a large scale global problem for a long time.
The drug administration covered more than 65% of citizens, according to the report. The first mass drug administration in Port-au-Prince took place from November 2011 through 2012. 71% of persons were taking albendazole.
It’s estimated that about 120 million people all over the world are suffering from lymphatic filariasis, and Haiti was among those 4 the most endemic. WHO estimates the elimination of the disease by 2020, due to mass administration of anthelmintic drugs. By 2011, at least one round of mass drug administration of albendazole and diethylcarbamazine (Hetrazan, Lederle) had been issued to all endemic areas in Haiti except for Port-au-Prince.
The researchers evaluated coverage in Port-au-Prince by conducting a stratified, three-stage cluster-sample survey in seven strata: internally displaced person (IDP) camps in six communes comprised one stratum, and non-IDP camp households in each of the six communes comprised six strata. A total of 6,345 adults answered for themselves and/or others in the household about taking the tablets, and 71% had taken the drugs.
The researchers found that 88% of the respondents knew about the mass drug administration before it began. Only half of the people who did not hear about it in advance took the tablets, compared with 74% of people who did hear about it in advance.
The coverage demonstrates that despite substantial obstacles posed by recent natural disasters and public health emergencies, Haiti has taken an important step toward meeting the challenge of lymphatic filariasis .
Dutasteride (brand name: Avodart), dual acting 5 alpha-reductase inhibitor in combination with alpha blocker tamsulosin (brand name: Flomax) have sown perfect results in continuous improvement in men with BPH and in patient-reported quality of life.
Jack Barkin, Assistant Professor of Surgery in the University of Toronto with his colleagues made a study, involved 4,800 men with moderate to severe BPH. The men were given dutasteride/tamsulosin combination, only dutasteride and the third group – tamsulosin monotherapy during four weeks.
The trial reviled that combination of Avodart and Flomax had much more improved symptoms and flow rate than results in men having single drug treatment.
After 3th month of combinational treatment patients found it significantly greater than the dutasteride therapy and from 9th month better than tamsulosin.
Dr. Barkin said this was the first trial demonstrating the significant benefits of the combinational treatment with a 5 alpha reductase inhibitor and alpha blocker, improving patient-reported quality of life.
BPH is a progressive and annoying disease having a considerable bed impact on quality of life. Botheing and interfering with daily activities are the main causes for BPH patients to run for healthcare. benign prostatic hyperplasia affects about 50% of men after 50, and almost 90% of men after 80.
The study was sponsored by GSK.